Robbie Henshaw will partner Bundee Aki at the Pool A decider of Ireland for his first taste of the World Cup in Japan at Center on Saturday.
The Irish and British Lions power has missed three of Irelands World Cup games so far, in training weeks later landing in Japan, having picked up a hamstring injury.
But the 26-year-old is prepared and healthy to fire to some match Ireland needs to win to guarantee their place at the quarter-finals.
The bulk of their large guns has rolled out to have the bodily and assaulting Samoans, though Jordan Larmour has set in at full-back in place of Rob Kearney.
Tadhg Beirne replenishes his Munster colleague Peter OMahony at flanker, together with boss Joe Schmidt eager to alleviate the workload on the British and Irish Lions back-rower.
While Joey Carbery carries a seat on the bench, with Ireland buoyed to have both play-makers back to full 26, johnny Sexton begins at fly-half .
Ireland: 15 Jordan Larmour, 14 Keith Earls, 13 Robbie Henshaw,12 Bundee Aki, 11 Jacob Stockdale, 10 Jonathan Sexton, 9 Conor Murray, 1 Cian Healy, 2 Rory Best (c), 3 Tadhg Furlong, 4 Iain Henderson, 5 James Ryan, 6 Tadhg Beirne, 7 Josh van der Flier, 8 CJ Stander
Replacements: 23 Andrew Conway, 16 Niall Scannell, 17 Dave Kilcoyne 19 Jean Kleyn, 20 Peter OMahony, 21 Luke McGrath, 22 Joey Carbery
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