Robbie Henshaw will Associate Bundee Aki in the Pool A decider of Ireland for his first taste of the World Cup at Center against Samoa on Saturday.
The British and Irish Lions power has missed three of Irelands World Cup games so much, in practice later landing in Japan, with picked up a hamstring injury.
But now the 26-year-old is healthy and ready to fire to some game Ireland should win to guarantee their place.
The majority of their large guns has gathered though Jordan Larmour has slotted in at full-back in place of Rob Kearney to take on the assaulting and physical Samoans.
Tadhg Beirne replaces his Munster colleague Peter OMahony in blindside flanker, together with manager Joe Schmidt eager to ease the workload on the Irish and British Lions back-rower.
Johnny Sexton starts at fly-half while Joey Carbery takes a seat on the bench, together with Ireland buoyed to have both back to full fitness.
Ireland: 15 Jordan Larmour, 14 Keith Earls, 13 Robbie Henshaw,12 Bundee Aki, 11 Jacob Stockdale, 10 Jonathan Sexton, 9 Conor Murray, 1 Cian Healy, 2 Rory Best (c), 3 Tadhg Furlong, 4 Iain Henderson, 5 James Ryan, 6 Tadhg Beirne, 7 Josh van der Flier, 8 CJ Stander
Replacements: 16 Niall Scannell, 17 Dave Kilcoyne, 18 Andrew Porter, 19 Jean Kleyn 21 Luke McGrath, 22 Joey Carbery, 23 Andrew Conway
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